<i>Dolichos lablab</i> L. extracts as pharmanutrient for stress-related mucosal disease in rat stomach

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Effect of chronic stress and L-carnitine on rat stomach.

BACKGROUND AND AIM L-Carnitine is an essential cofactor in the mitochondrial transfer of fatty acids, and it is also a scavenger of free radicals in mammalian tissues. The aim of the study was to determine the effect of L-carnitine on chronic restraint stress-induced gastric mucosal injury. METHODS Wistar rats were applied restraint stress (1 h/day) and L-carnitine (50 mg/kg) for 21 days. The...

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BACKGROUND The term stress-related mucosal disease (SRMD) represents a continuum of conditions ranging from stress-related injury (superficial mucosal damage) to stress ulcers (focal deep mucosal damage). Caused by mucosal ischemia, SRMD is most commonly seen in critically ill patients in the intensive care unit (ICU). Prophylaxis of stress ulcers may reduce major bleeding but has not yet been ...

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ژورنال

عنوان ژورنال: Journal of Clinical Biochemistry and Nutrition

سال: 2020

ISSN: 0912-0009,1880-5086

DOI: 10.3164/jcbn.20-11